Telomere length regulates ISG15 expression in human cells
نویسندگان
چکیده
منابع مشابه
Telomere length regulates ISG15 expression in human cells
Endogenous genes regulated by telomere length have not previously been identified in human cells. Here we show that telomere length regulates the expression of interferon stimulated gene 15 (ISG15, 1p36.33). ISG15 expression (RNA and protein) increases in human cells with short telomeres, and decreases following the elongation of telomeres by human telomerase reverse transcriptase (hTERT). The ...
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ژورنال
عنوان ژورنال: Aging
سال: 2009
ISSN: 1945-4589
DOI: 10.18632/aging.100066